Compute the \(p_{SNP} \times p_{SNP}\) variance-covariance matrix of SNP dosages. This is an estimator of the LD between loci within a given population.

genoVarCovarMatFunc(Z)

Arguments

Z

column-centered matrix of SNP dosages. Assumes SNPs in Z were originally coded 0, 1, 2 were column centered.

Value

NOTE: this matrix is going to be big in practice. The \(p_{SNP} \times p_{SNP}\) variance-covariance matrix of SNP dosages. may be worth computing in an R session using multi-threaded BLAS