Compute the \(p_{SNP} \times p_{SNP}\) variance-covariance matrix of SNP dosages. This is an estimator of the LD between loci within a given population.
genoVarCovarMatFunc(Z)
column-centered matrix of SNP dosages. Assumes SNPs in Z were originally coded 0, 1, 2 were column centered.
NOTE: this matrix is going to be big in practice. The \(p_{SNP} \times p_{SNP}\) variance-covariance matrix of SNP dosages. may be worth computing in an R session using multi-threaded BLAS
Other helper:
backsolveSNPeff()
,
centerDosage()
,
crosses2predict()
,
dose2domDevGenotypic()
,
dose2domDev()
,
effectsArray2list()
,
genmap2recombfreq()
,
getAF()
,
getMAF()
,
getPropHom()
,
intensity()
,
kinship()
,
maf_filter()
,
quadform()
,
remove_invariant()